1.Jiao L, Han Q, Xu Y, Chen W, Lu T, Zhang H, Zhou A, Wu W, Zhang Y, Li A, Li Y. Exosomal circDB enhances ischemic muscle repair via the miR-34a/USP7/Notch1 signaling pathway. Regenerative Therapy, 2025; 30: 616-628
2.Wang Y, Wu W, Xu Y, Wu C, Han Q, Lu T, Zhang H, Jiao L, Zhang Y, Liu B, Yu XY, Li Y. Ncl liquid-liquid phase separation and SUMOylation mediate the stabilization of HIF-1α expression and promotes pyroptosis in ischemic hindlimb. BBA-Molecular Basis of Disease, 2025; 1871: 167706
3.Li Y, Liu Y, Yu XY, Xu Y, Pan X, Sun Y, Wang Y, Song YH, Shen Z. Membraneless organelles in health and disease: Exploring the molecular basis, physiological roles, and pathological implications. Signal Transduction and Targeted Therapy. 2024; 9(1):305
4.Wang Y, Tu J, Wu W, Xu Y, Li Y, Pan X,Liu B, Lu T, Han Q, Zhang H, Jiao L, Zhang Y, Yu XY, Shen Z, Li Y. The orchestration of cell-cycle reentry and ribosome biogenesis network is critical for cardiac repair. Theranostics. 2024; 14(10):3927-3944
5.Geng S, Liu SB, He W, Pan X, Sun Y, Xue T, Han S, Lou J, Chang Y, Zheng J , Shi X, Li Y, Song YH. Deletion of TECRL promotes skeletal muscle repair by up-regulating EGR2.Proc Natl Acad Sci U S A. 2024; 121(21):e2317495121
6.Lu L, Liu F, Wu W, Zhang Y, Liu B, Han Q, Lu T, Zhang H, Yu XY, Li Y. Stem cell-derived exosomes prevent the development of thoracic aortic aneurysm/dissection by inhibiting AIM2 inflammasome and pyroptosis. Extracellular Vesicle. 2024; 4: 100046
7.Lou J, Geng S, He W, Liu S, Shi X, Chang Y, Han S, Qian P, Song YH, Amin H, Li Y, Zhou J. Zyxin inhibits the EMT process in gastric cancer by up-regulating SIRT1. MedComm. 2023; 4(5):e357
8.Zhang Y, Tu J, Li Y, Wang Y, Lu L, Wu C, Yu XY, Li Y (corresponding author). Inflammation macrophages contribute to cardiac homeostasis. Cardiology Plus.2023; 8(1):6-17
9.Hao Y, Xue T, Liu, SB, Geng S, Shi X, Qian P, He W; Zheng J, Shi T, Wang G, Wang X, Wang Y, Li Y, Song YH. Loss of CRY2 promotes regenerative myogenesis by enhancing PAX7 expression and satellite cell proliferation. MedComm. 2023; 4(1):e202
10.Jiao L, Liu Y, Yu XY, Pan X, Zhang Y, Tu J, Song YH, Li Y. Ribosome biogenesis in disease: new players and therapeutic targets. Signal Transduction and Targeted Therapy. 2023; 8(1):15
11.Zhang Y, Wu W, Pan X, Wang Y, Wu C , Lu L, Yu XY, Li Y. Extracellular vesicles as novel therapeutic targets and diagnosis markers. Extracellular Vesicle. 2022; 1: 100017
12.Ding F, Lu L, Wu C, Pan X, Liu B, Zhang Y, Wang Y, Wu W, Yan B, Zhang Y, Yu XY, Li Y. circHIPK3 prevents cardiac senescence by acting as a molecular glue to recruit ubiquitin ligase to degrade HuR. Theranostics. 2022; 12(17):7550-7566
13.Zheng J, Lou J, Li Y, Qian P, He W, Hao Y, Xue T, Li Y, Song YH. Satellite cell-specific deletion of Cipc alleviates myopathy in mdx mice. Cell Rep. 2022; 39(11):110939
14.Zhang Y, Jiao L, Lu L, Wu C, Tu J, Li Y, Wang Y, Ding F, Luo W, Chen W, Shen Z, Song YH,, Li Y. The mechanisms underlying the beneficial effects of stem cell-derived exosomes in repairing ischemic tissue injury. J Cardiovasc Transl Res. 2022; 15(3):524-534
15.Han C, Liu F, Zhang Y, Chen W, Luo W, Ding F, Lu L, Wu C, Li Y. Human umbilical cord mesenchymal stem cell derived exosomes delivered using silk fibroin and sericin composite hydrogel promote wound healing. Frontiers in Cardiovascular Medicine, 2021; 8:713021
16.Li Y, Huang H, Liu B, Zhang Y, Pan X, Yu XY, Shen Z, Song YH. Inflammasomes as therapeutic targets in human diseases. Signal Transduction and Targeted Therapy, 2021; 6(1):247
17.Wang Y, Xie W, Liu B, Huang H, Luo W, Zhang Y, Pan X, Yu XY, Shen Z, Li Y. Stem cell-derived exosomes repair ischemic muscle injury by inhibiting the tumor suppressor Rb1-mediated NLRP3 inflammasome pathway. Signal Transduction and Targeted Therapy, 2021; 6:121
18.Li Y, Ding FZ, Shen ZY. Letter by Li et al Regarding Article, “Small Extracellular Microvesicles Mediated Pathological Communications Between Dysfunctional Adipocytes and Cardiomyocytes as a Novel Mechanism Exacerbating Ischemia/Reperfusion Injury in Diabetic Mice”. Circulation, 2020; 142(7): e95–e96
19.Yan B, Zhang Y, Liang C, Liu B, Ding FZ, Wang YL, Zhu B, Zhao RZ, Yu XY, Li Y. Stem cell-derived exosomes prevent pyroptosis and repair ischemic muscle injury through a novel exosome/circHIPK3/ FOXO3a pathway.Theranostics, 2020; 10(15): 6728-6742
20.Zhang Y, Wang Y, Shao L, Pan X, Liang C, Liu B, Zhang Y, Xie W, Yan B, Liu F, Yu XY, Li Y. Knockout of beta-2 microglobulin reduces stem cell-induced immune rejection and enhances ischemic hindlimb repair via exosome/miR-24/Bim pathway. J of Cellular and Molecular Medicine, 2020; 24(1):695-710
21.Li Y, Shen ZY, Yu XY. Letter Regarding Article, Dectin-1 Contributes to Myocardial Ischemia/Reperfusion Injury by Regulating Macrophage Polarization and Neutrophil Infiltration. Circulation, 2019; 140(5):e177-e178
22.Shao LB, Zhang Y, Pan XB, Liu B, Liang C, ZhangYQ, Wang YL, Yan B, Xie WP, Sun Y, Shen ZY, Yu XY, Li Y. Knockout of beta-2 microglobulin enhances cardiac repair by modulating exosome imprinting and inhibiting stem cell-induced immune rejection. Cellular and Molecular Life Sciences, 2020, 77(5):937-952
23.Han CS, Zhou J, Liu B, Liang C, Pan XB, Zhang Y, Zhang YQ, Wang YL, Shao LB, Zhu B, Wang JJ, Yin Q, Yu XY, Li Y. Delivery of miR-675 by stem cell-der ived exosomes encapsulated in silk fibroin hydrogel prevents aging-induced vascular dysfunction in mouse hindlimb. Materials Science & Engineering C, 2019; 99:322-332
24.Han CS, Zhou J, Liu B, Liang C, Liu B, Pan XB, Zhang Y, Wang YL, Yan B, Xie WP, Liu F, Yu XY, Li Y. Human umbilical cord mesenchymal stem cell derived exosomes encapsulated in functional peptide hydrogels promote cardiac repair. Biomaterials Science, 2019; 7(7):2920-2933
25.Zhu B, Zhang L, Liang C, Liu B, Pan X, Wang Y, Zhang YQ, Zhang Y, Xie W, Yan B, Liu F, Yip H, Yu XY, Li Y. Stem Cell-Derived Exosomes Prevent Aging-Induced Cardiac Dysfunction through Novel Exosome/LncRNA MALAT1/NF-κB/TNF-α Signaling Pathway. Oxidative Medicine and Cellular Longevity , 2019; Article ID 9739258
26.Li Y, Liu B and Liang C. Letter by Li et al Regarding Article, Cardiac Fibroblast-Specific Activating Transcription Factor 3 Protects Against Heart Failure by Suppressing MAP2K3-p38 Signaling. Circulation. 2017; 136: 2092-2093
27.Li Y, Zhou J, Song YH, Yu XY. Dominant and recessive imprinting of exosomes from parent cells. Nature Reviews Cardiology, 2017, 14(8): 491
28.Shao L, Zhang Y, Lan B, Wang J, Zhang Z, Zhang L, Xiao P, Meng Q, Geng YJ, Yu XY and Li Y. MiRNA-Sequence Indicates That Mesenchymal Stem Cells and Exosomes Have Similar Mechanism to Enhance Cardiac Repair. Biomed Res Int. 2017; 2017: 4150705
29.Shen C, Zhou J, Wang X, Yu XY, Liang C, Liu B, Pan X, Zhao Q, Song JL, Wang J, Bao M, Wu C, Li Y and Song YH. Angiotensin-II-induced Muscle Wasting is Mediated by 25-Hydroxycholesterol via GSK3beta Signaling Pathway. EBioMedicine. 2017; 16: 238-250
30.Li Y, Song YH, Liu B and Yu XY. The potential application and challenge of powerful CRISPR/Cas9 system in cardiovascular research. Int J Cardiol. 2017; 227: 191-193
31.Li Y, Song YH and Yu XY. Letter by Li et al Regarding Article, MiR-125b Is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis. Circulation. 2016; 133: e713
32.Zhou J, Liu B, Liang C, Li Y and Song YH. Cytokine Signaling in Skeletal Muscle Wasting. Trends Endocrinol Metab. 2016; 27: 335-347
33.Li Y, Shen Z and Yu XY. Transport of microRNAs via exosomes. Nat Rev Cardiol. 2015; 12: 198
1.CRISPR技术编辑并用IGF优化的异体间充质干细胞的制备方法及在治疗心梗中应用，发明人：李杨欣；沈振亚；邵联波，专利号：ZL 2016 1 0297972.0（已授权；已转化）
2.间充质干细胞分泌的外泌小体治疗心肌梗死的新用途，发明人：李杨欣，申请公布号：CN105395571A
3.多肽、重组DNA分子、重组载体、外泌体及其应用，发明人：李杨欣；邵联波；沈振亚，专利号：ZL 2018 1 0447876.9（已授权）
4.一种缓释外泌体的多肽纳米纤维水凝胶及其制备方法与应用，发明人：李杨欣；韩超珊，专利号：ZL 2018 1 0820335.6（已授权）
5.丝素水凝胶包裹的过表达ncRNA的MSC外泌体制备方法与在抗后肢衰老中的应用，发明人：李杨欣；韩超珊，专利号：ZL 2018 1 0140513.0（已授权；已转化）
6.一种带有母系印记的温敏感外泌体体系及其制备方法和应用，发明人：李杨欣；刘冯；沈振亚；张瑜，申请公布号：CN111450117A
7.外泌体在胸主动脉夹层 /动脉瘤中的作用，发明人：李杨欣；刘冯；沈振亚；张瑜，专利号：ZL 2021 1 1444763.1（已授权）
基金支持
2.国自然基金面上项目
3.博士后合作导师专项经费
4.放射医学与辐射防护国家重点实验室资助项目
5.国自然基金重大研究（培育）项目
6.江苏省“六大人才高峰”创新团队
7.江苏省双创团队
8.江苏省重点研发计划（社会发展）项目
9.苏州市民生科技项目
10.苏州市高等院校、科研院所紧缺高层次人才
11.江苏省双创人才计划项目
12.苏州大学启动经费
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